How long until testosterone replacement therapy starts working?

We know that testosterone has a wide-range of effects in men. But how long after you begin testosterone replacement therapy until the testosterone treatment's maximum effects are achieved? The Scientific Affairs team at Men's Healthcare in Germany recently asked that same question and their results were quite interesting.

With testosterone replacement therapy, effects with sexual interest appear after 3 weeks, and plateau at 6 weeks, with no further increments expected beyond. Changes in erections/ejaculations may require up to 6 months of testosterone replacement therapy. Effects on quality of life manifest within 3-4 weeks, but maximum benefits take longer. Effects on depressive mood become detectable after 3-6 weeks with a maximum after 18-30 weeks. Effects on erythropoiesis (the process by which red blood cells are produced) are evident at 3 months, peaking at 9-12 months. Prostate-specific antigen and volume rise, marginally, plateauing at 12 months; further increase should be related to aging rather than testosterone replacement therapy. Effects on lipids appear after 4 weeks, maximal after 6-12 months. Insulin sensitivity may improve within few days, but effects on glycemic control become evident only after 3-12 months. Changes in fat mass, lean body mass, and muscle strength occur within 12-16 weeks, stabilize at 6-12 months, but can marginally continue over years. Effects on inflammation occur within 3-12 weeks. Effects on bone are detectable already after 6 months while continuing at least for 3 years. Read the full study here.

These results show that while the effectiveness time with testosterone replacement therapy varies from symptom to symptom, it does take only a short time to see improvements compared dealing with the effects of low testosterone for a lifetime. Questions about Testosterone Replacement Therapy? Get them answered here!

Testosterone Replacement Therapy

Low testosterone can be easily diagnosed with a simple blood test and treated with testosterone replacement therapy to bring your testosterone levels back to normal. The testosterone replacement therapy options available are:

  • intramuscular injections
  • sublingual troches taken daily
  • testosterone cream that are applied daily to the shoulders, upper arms, or abdomen

Each of these options provides adequate levels of hormone replacement. Each has side effects and advantages and disadvantages.The choice of hormone replacement therapy is best made with a thorough discussion between you and Dr. Bird. This can be discussed at the free testosterone replacement therapy consultation.

Schedule your free testosterone replacement therapy consultation

Call 480-839-4131 or fill out the webform located throughout the site to schedule your free consultation. We look forward to meeting you and working with you in the future.

We serve patients in the Phoenix AZ area including Tempe, Chandler, Gilbert, Mesa, Scottsdale, Ahwatukee, Peoria, Glendale, Avondale and Fountain Hills. We work with out-of-town and out-of-state patients as well via web conferencing options, follow-up telephone calls and emails. All patients, regardless of location, always work directly with Dr. Bird to ensure patient safety and confidentiality.